Development and validation of LC–MS-based bioanalytical methods for oligonucleotide therapeutics: points to consider

已完结 10 由 321 发布于 2026/9/17 15:34:38

DOI:10.1016/j.dmpk.2026.101545
作者：Yuchen Sun,&nbsp;Kosuke Saito,&nbsp;Shin-ichiro Nitta,&nbsp;Ryoya Goda,&nbsp;Yuki Kishino,&nbsp;Hisashi Fujita,&nbsp;Masaaki Kakehi,&nbsp;Yoshiharu Hayashi,&nbsp;Satosh
文献类型：期刊论文
补充材料：只需要正文

Elsevier

Abstract：The analysis of oligonucleotide therapeutics, including antisense oligonucleotides and siRNAs, using existing bioanalytical methods presents unique analytical challenges owing to their disti

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