Discovery of a prominent dual-target DDR1/EGFR inhibitor aimed DDR1/EGFR-positive NSCLC

已完结 10 由 YAJ 发布于 2026/9/20 10:40:35

DOI:10.1016/j.bioorg.2024.107500
作者：Xuebao Wang ,?Ying Lu ,?Siyu Chen ,?Zhaojingtao Zhu ,?Yanneng Fu ,?Jinxia Zhang ,?Jiale He ,?Lu Huang ,?Lihong Luo ,?Weiting Guo ,?Zhouyang Xu ,?Zixin Xie ,?Xuemei Xu ,?Yuan Zhang ,?Faqing Ye ,?Shumei
文献类型：期刊论文
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Elsevier

Abstract：This study aimed to develop the first dual-target small molecule inhibitor concurrently targeting Discoidin domain receptor 1 (DDR1) and Epidermal growth factor receptor (EGFR), which play a

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