Abstract 4891: Ifinatamab deruxtecan (I-DXd), a novel B7-H3-targeting antibody-drug conjugate, demonstrates efficient payload delivery into tumor through target-dependent internalization

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DOI:10.1158/1538-7445.am2023-4891
作者：L. Katsumata, Tsuneo Deguchi, J. Hasegawa, M. Yamato, Y. Nishiya, Akiko Watanabe, T. Honda, M. Minami, N. Kasanuki, T. Maejima, Sumie Muramatsu, 
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American Association for Cancer Research (AACR)

Abstract： Ifinatamab deruxtecan (I-DXd; DS-7300) is a novel ADC which consists of an anti-B7-H3 antibody linked with a DNA topoisomerase I inhibiting anti-tumor agent, DXd. I-DXd has demonstrated po

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