Development of potent and selective ENPP1 inhibitors based on imidazo[1,2-a]pyrazine and pyrazine scaffolds for cancer immunotherapy.

已完结 10 由 123 发布于 2026/8/31 17:18:18

DOI:10.1016/j.ejmech.2026.119274
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1016/j.ejmech.2026.119274

Elsevier

Abstract：In this study, new imidazo[1,2-a]pyrazine derivative 15 (YS3074) and pyrazine derivative 17 (YS3375) are identified and optimized as potent and selective ENPP1 inhibitors. Compounds 15 and 1

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