mRNA lipid nanoparticle cancer vaccine platform delivering multiple STING activators for enhanced antitumor activity.

已完结 20 由 lll 发布于 2026/8/31 12:16:26

DOI:10.1073/pnas.2525718123
作者：Ye Zeng,Junchao Xu,Jinjin Wang,Lulu Xue,Jiageng Liu,Hannah C Geisler,Xu Ma,Jilian R Melamed,Qiangqiang Shi,Marshall S Padilla,Zhangyi Luo,Jingcheng Zhu,Ajay S Thatte,Christian G Figueroa-Espada,Melgio
文献类型：期刊论文
补充材料：仅需补充材料
文献链接：https://doi.org/10.1073/pnas.2525718123

Proceedings of the National Academy of Sciences of the United States of America (PNAS)

Abstract：mRNA-based cancer vaccines offer a modular and safe platform to elicit antitumor immunity, yet their efficacy is often limited by inefficient mRNA delivery and inadequate dendritic cell (DC)

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