Fullerenols hijack lysosomes to disrupt inter-organellar crosstalk and block autophagy pre-activated by mTOR inhibitors for cancer cell PANoptosis

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DOI:10.1016/j.scib.2025.02.034
作者：Hedong Qi ,?Xue Li ,?Jing Ma ,?Jiacheng Sun ,?Yating Liu ,?Xin Wang ,?Kelong Fan ,?Chunying Shu ,?Chunru Wang
文献类型：期刊论文
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Elsevier

Abstract：Subcellular inter-organellar crosstalk among lysosome, endoplasmic reticulum (ER), and mitochondrion is crucial for cancer cell survival and is a promising target in cancer treatment; howeve

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