Anti-rituximab antibodies affect pharmacokinetics and pharmacodynamics of rituximab in children with immune-mediated diseases.

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DOI:10.55563/clinexprheumatol/ftira8
作者：Ilja Oomen,?Amara Nassar-Sheikh Rashid,?Antonia H M Bouts,?Samantha C Gouw,?Taco W Kuijpers,?Theo Rispens,?Annick de Vries,?Gertjan Wolbink,?J Merlijn van den Berg,?Dieneke Schonenberg-Meinema
文献类型：期刊论文
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Abstract：Objectives: Rituximab (RTX) is a chimeric monoclonal CD20-antibody. Lack of efficacy has been suggested to be related to the presence of anti-drug antibodies (ADA). The aims of this study we

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