Manipulation of protein translation and stem cell self-renewal by CRISPR activation of rRNA transcription

已完结 10 由魁星北斗发布于 2026/9/6 16:49:00

DOI:10.1126/science.aeh1348
作者：Maximilian Wiesbeck, Emilie L. Alard, Florencia Merino, Niti Chowdhury, Luisa Egert, Anna Danese, Simon Imhof, Matilde Iraci Borgia, Akshaya Rajan, Nadine Fernandez-Novel Marx, Edina Kepesidis, Anna K
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：Ribosomal RNA (rRNA) transcription rates vary during development, and their dysregulation is linked to diseases such as cancer and ribosomopathies. Owing to their high abundance and genomic

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