FASN Inhibition Decreases MHC-I Degradation and Synergizes with PD-L1 Checkpoint Blockade in Hepatocellular Carcinoma.

已完结 20 由达姆发布于 2026/9/9 9:10:45

DOI:10.1158/0008-5472.CAN-23-0966
作者：Jiao Huang,?Wai Ying Tsang,?Xiao-Na Fang,?Yu Zhang,?Jie Luo,?Lan-Qi Gong,?Bai-Feng Zhang,?Ching Ngar Wong,?Zhi-Hong Li,?Bei-Lei Liu,?Jin-Lin Huang,?Yu-Ma Yang,?Shan Liu,?Liu-Xian Ban,?Yiu Hong Chan,?X
文献类型：期刊论文
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American Association for Cancer Research (AACR)

Abstract：Immune checkpoint inhibitors (ICI) transformed the treatment landscape of hepatocellular carcinoma (HCC). Unfortunately, patients with attenuated MHC-I expression remain refractory to ICIs,

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