Scanning nitrogen in sp3-rich scaffolds enabled by carbonyl-to-nitrogen atom swap

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DOI:10.1126/science.aef0610
作者：Zining Zhang,?Zhehan Liang,?Rong Ye,?Guangbin Dong
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：Medicinal chemistry campaigns routinely require access to series of saturated nitrogen heterocycle (SNH)–based analogs that place nitrogen at different positions to probe structure-activity

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