Design of Novel Exatecan-Amide Linker-Payloads for the Development of Stable, Low-Aggregating, and Highly Efficacious Antibody-Drug Conjugates

已完结 20 由微笑的鱼发布于 2026/5/9 13:33:01

DOI:10.1021/acs.jmedchem.5c03706
文献类型：期刊论文
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文献链接：https://doi.org/10.1021/acs.jmedchem.5c03706

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Abstract：Through their uniquely effective combination of a target-selective antibody and a highly potent cytotoxic payload, antibody-drug conjugates (ADCs) are transforming cancer therapy. Nonetheles

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