Wholly enzymatic programmable sulfation in nonanimal heparin synthesis.

待确认 10 由 lrz07 发布于 2026/6/20 11:15:08

DOI:10.1016/j.tibtech.2026.04.028
作者：Yi Li, Jian-Qun Deng, An-Qi Wang, Si-Yu Xin, Li-Li Sheng, Yu-Han Zhao, Xin-Yu Li, Chao-Yue Li, Feng-Shan Wang, Hua-Rong Shao, Ju-Zheng Sheng
文献类型：期刊论文
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Elsevier

Abstract：Heparin is a critically important clinical anticoagulant. The biosynthesis of heparin using Escherichia coli-based multienzyme cascades represents a promising alternative to animal-derived p

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