Synthesis and structure-activity relationship studies of 2,4-thiazolidinediones and analogous heterocycles as inhibitors of dihydrodipicolinate synthase

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DOI:10.1016/j.bmc.2021.116518
作者：Rebecca M. Christoff , Tatiana P. Soares da Costa , Saadi Bayat , Jessica K. Holien , Matthew A. Perugini , Belinda M. Abbott
文献类型：期刊论文
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Elsevier

Abstract：Dihydrodipicolinate synthase (DHDPS), responsible for the first committed step of the diaminopimelate pathway for lysine biosynthesis, has become an attractive target for the development of

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