CD39+CD49a+CD103+ cytotoxic tissue-resident natural killer cells infiltrate and control solid epithelial tumor growth in mice

待确认 10 由 solitude 发布于 2026/6/21 23:59:37

DOI:10.1126/scitranslmed.adw5567
作者：Nina B. Horowitz, Imran A. Mohammad, June Ho Shin, John W. Hickey, Peter Chockley, Gail Snyder, Chen Chen, Keene Lee, Krishna Sharma, Quan Tran, Anahi
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American Association for the Advancement of Science (AAAS)

Abstract：Human tissue-resident natural killer (NK) cells (trNK cells), broadly defined by markers of tissue residency, such as CD49a [integrin α1 (ITGA1)] and CD103 [integrin αE (ITGAE)], are increas

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