Efficient export of prefolded, disulfide-bonded recombinant proteins to the periplasm by the Tat pathway in Escherichia coli CyDisCo strains.

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DOI:10.1002/btpr.1858
作者：Cristina F R O Matos, Colin Robinson, Heli I Alanen, Piotr Prus, Yuko Uchida, Lloyd W Ruddock, Robert B Freedman, Eli Keshavarz-Moore
文献类型：期刊论文
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Wiley

Abstract：Numerous high-value therapeutic proteins are produced in Escherichia coli and exported to the periplasm, as this approach simplifies downstream processing and enables disulfide bond formatio

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