Copper-catalysed homo-Mannich reaction of cyclopropanol for chiral piperidine synthesis

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DOI:10.1038/s41929-025-01432-4
作者：Yankun Zhao,?Wenxuan Lin,?Yulian Zhang,?Guangcheng Pu,?Zhuoyuan Jian,?Hongya Yan,?Ling He,?Chengyang Wang,?Qiuyuan Tan,?Yu Lan,?Min Zhang
文献类型：期刊论文
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Nature

Abstract：The Mannich reaction represents one of the most fundamental reactions for the stereoselective synthesis of β-amino-carbonyl compounds and has been broadly applied in organic synthesis. In co

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