Krüppel-like factor 2 programs early exhausted T cell states and restrains antiviral immunity.

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DOI:10.1016/j.immuni.2026.03.029
文献类型：期刊论文
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文献链接：https://doi.org/10.1016/j.immuni.2026.03.029

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Abstract：A key challenge in improving T cell-mediated immunotherapies is defining the factors that regulate functional versus exhausted T cell fates. Through multi-round in vivo CRISPR screens in chr

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