Investigating Genetic Risk to Oxaliplatin-Induced Sinusoidal Obstruction Syndrome in Colorectal Cancer Through Routinely Available Next-Generation Sequencing Data

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DOI:10.1016/j.modpat.2026.100988
作者：Mengxue Zhang ,?Peng Wang ,?Yang Kong ,?Daniela D. Gaudio ,?Nick Parente ,?Ashley Hayden ,?Namrata Setia ,?John Hart
文献类型：期刊论文
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Elsevier

Abstract：Sinusoidal obstruction syndrome (SOS) is a known adverse effect of oxaliplatin, causing significant morbidity and cessation of chemotherapy. Recent studies suggest single-nucleotide polymorp

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