A sensitive LC?MS/MS method for the simultaneous quantification of hexosylceramides and hexosylsphingosines, their precursors and metabolites in cells, plasma, and tissue homogenates

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DOI:10.1007/s00216-026-06485-3
作者：Michele Iannone,?Tine Loomans,?Sara Gorremans,?Elien Grajchen,?Celine Deneubourg,?Brian Hrupka,?Luc Ver Donck,?Alexis Bretteville,?Diederik Moechars,?Rob J. Vreeken,?Farid Jahouh
文献类型：期刊论文
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Springer

Abstract：Hexosylceramides (HexCers) and hexosylsphingosines (HexSphs) are bioactive glycosphingolipids implicated in neurodegenerative diseases such as Parkinson’s disease (PD), Gaucher disease, and

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