Understanding and Modulating Opalescence and Viscosity in a Monoclonal Antibody Formulation

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DOI:10.1002/jps.21797
作者：Branden A Salinas 1, Hasige A Sathish, Steven M Bishop, Nick Harn, John F Carpenter, Theodore W Randolph
文献类型：期刊论文
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文献链接：https://doi.org/10.1002/jps.21797
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Abstract：Opalescence and high viscosities can pose challenges for high concentration formulation of antibodies. Both phenomena result from protein–protein intermolecular interactions that can be modu

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