A cholinergic checkpoint controls autoantibody selection via somatic hypermutation in lupus germinal centers.

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DOI:10.1038/s41423-026-01444-5
作者：Jin Li,?Yimei Lai,?Huijin Zou,?Yichao Qian,?Xinyuan Ruan,?Lili Zhuang,?Zhangmei Lin,?Yumeng Wang,?Niansheng Yang,?Shuyi Wang,?Hui Zhang
文献类型：期刊论文
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Springer

Abstract：Systemic lupus erythematosus (SLE) pathogenesis involves the dysregulated production of mutated, high-affinity autoantibodies, a process primarily orchestrated within germinal centers (GCs).

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