Prophylactic (R,S)-Ketamine and (2S,6S)-Hydroxynorketamine Decrease Fear Expression by Differentially Modulating Fear Neural Ensembles

已完结 10 由 Calor 发布于 2026/6/4 10:19:07

DOI:10.1016/j.biopsych.2024.09.024
作者：Alessia Mastrodonato ,?Michelle Jin ,?Noelle Kee ,?Marcos Lanio ,?Juliana Tapia ,?Liliette Quintana ,?Andrea Mu?oz Zamora ,?Shi-Xian Deng ,?Xiaoming Xu ,?Donald W. Landry ,?Christine A. Denny
文献类型：期刊论文
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Elsevier

Abstract：BackgroundWe previously reported that a single injection of (R,S)-ketamine or its metabolite (2S,6S)-hydroxynorketamine (HNK) prior to stress attenuated learned fear. However, whether these

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