Kilo-Scale-Enabled Route toward PF-07907063, a Type II Brain Penetrant cMET Inhibitor

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DOI:10.1021/acs.oprd.4c00441
作者：Grace McKenna, Cole Cruz, Bryon Simmons, James T. Brewster, II, Anna M. Benz-Weeden, Thomas A. Brandt, Quinn A. Bumpers, Adam Cook, Mohamed Saad Abdullah Elsayed, Daniel Golec, Nicholas Lewandowski, P
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American Chemical Society (ACS)

Abstract：New synthetic methodologies that access complex saturated building blocks enable the synthesis of drug molecules with unique properties. Here, we report collaborative efforts between Pfizer’

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