Riplet promotes lipid metabolism changes associated with CD8 T cell exhaustion and anti–PD-1 resistance in hepatocellular carcinoma

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DOI:10.1126/sciimmunol.ado3485
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1126/sciimmunol.ado3485

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Abstract：The overall response rate to immunotherapy is modest in hepatocellular carcinoma (HCC), and immunotherapy resistance mechanisms are incompletely understood. We report that the E3 ubiquitin l

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