Programmable RNA translation through deep learning-driven IRES discovery and de novo generation

已完结 10 由 study_lw 发布于 2026/5/10 20:18:41

DOI:10.1038/s42256-026-01213-z
作者：Yanyi Chu, Di Yin, Dan Yu, Guangxue Xu, Junze Zhang, Xiaotong Wang, Yue Shen, Yupeng Li, Ning Zhao, Yi Zhu, Jason Zhang, Hani Goodarzi, Meng
文献类型：期刊论文
补充材料：只需要正文

Nature

Abstract：The precise control of protein expression is a major bottleneck in the development of RNA therapeutics. Internal ribosome entry sites (IRES) overcome traditional limitations by enabling cap-

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