Activation of sclerostin inhibits Isg20-Mediated aerobic glycolysis ameliorating renal Fibrosis: the renoprotective mechanism of hederagenin in CKD

已完结 10 由 Tony 发布于 2026/3/4 14:55:26

DOI:10.1016/j.redox.2025.103762
作者：Rang-yue Han ,?Rui-zhi Tan ,?Ling-hui Xu ,?Jing-yi Lin ,?Tong Li ,?Hong-wei Su ,?Ping Li ,?Peng Liu ,?Hui-yao Lan ,?Li Wang
文献类型：期刊论文
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Elsevier

Abstract：Sclerostin (Sost) functions as an inhibitor of the Wnt/β-catenin signaling pathway, which is known to promote kidney cell epithelial-to-mesenchymal transition (EMT), and fibrosis in chronic

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