Emerging trends in the characterization of oligonucleotide diastereomers

已完结 10 由 Xinliang 发布于 2026/3/10 12:39:37

DOI:10.1016/j.chroma.2025.466308
作者：Alexandre Goyon,?Daniel Ngoc Nguyen,?Kelly Zhang
文献类型：期刊论文
补充材料：只需要正文

Elsevier

Abstract：Chemical modifications have enabled the use of oligonucleotides as therapeutic drugs. However, they also complicate their analytical characterization. Phosphorothioate (PS)-modified oligonuc

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