Synthesis and Evaluation of Three Azide-Modified Disaccharide Oxazolines as Enzyme Substrates for Single-Step Fc Glycan-Mediated Antibody-Drug Conjugation

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DOI:10.1021/acs.bioconjchem.2c00142
作者：Xiao Zhang, Chong Ou, Huiying Liu and Lai-Xi Wang*, 
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Antibody-drug conjugates (ADCs) hold great promise for targeted cancer cell killing. Site-specific antibody-drug conjugation is highly desirable for synthesizing homogeneous ADCs with optima

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