Single intramuscular injection of self-amplifying RNA of Nppa to treat myocardial infarction

已完结 10 由柚子发布于 2026/3/12 11:08:12

DOI:10.1126/science.adu9394
作者：Kaiyue Zhang, Hongyan Tao, Dashuai Zhu, Zhang Yue, Shiqi Hu, Yiping Wu, Na Yan, Yilan Hu, Shuo Liu, Mengrui Liu, Torsten Peter Vahl, Lauren Sharan Ranard, Xiao Cheng, Alexander Romanov, Jiaming Liu, S
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：Self-amplifying RNA (saRNA) enables sustained protein expression from a single administration. In this study, we developed an intramuscular saRNA-lipid nanoparticle (saNppa-LNP) therapy enco

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