CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity

已完结 20 由紫梦若雪发布于 2026/6/12 16:33:12

DOI:10.1038/s41587-019-0192-1
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1038/s41587-019-0192-1

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Abstract：Chimeric antigen receptor (CAR)-T-cell therapy for solid tumors is limited due to heterogeneous target antigen expression and outgrowth of tumors lacking the antigen targeted by CAR-T cells

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