Hexokinase dissociation from mitochondria promotes oligomerization of VDAC that facilitates NLRP3 inflammasome assembly and activation

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DOI:10.1126/sciimmunol.ade7652
作者：Sung Hoon Baik, V. Krishnan Ramanujan, Courtney Becker, Sarah Fett, David M. Underhill, Andrea J. Wolf
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：NLRP3 inflammasome activation is a highly regulated process for controlling secretion of the potent inflammatory cytokines IL-1β and IL-18 that are essential during bacterial infection, ster

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