Programmable genome editing in human cells using RNA-guided bridge recombinases

已完结 10 由木子发布于 2026/2/8 11:02:26

DOI:10.1126/science.adz1884
作者：Oana Pelea, András Tálas, Javier Fernández Carrera, Nicolas Mathis, Lilly van de Venn, Charles D. Yeh, Péter I. Kulcsár, Kim F. Marquart, Yanik Weber, Saskia E. Gerecke, Isabelle F. Harvey-Seutch
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：Site-specific insertion of gene-sized DNA fragments remains an unmet need in the field of genome editing. IS110-family serine recombinases have recently been shown to mediate programmable DN

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