Genetically Engineered Bacteria as A Living Bioreactor for Monitoring and Elevating Hypoxia-Activated Prodrug Tumor Therapy

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DOI:10.1002/adhm.202402272
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1002/adhm.202402272

Wiley

Abstract：Tirapazamine (TPZ), an antitumor prodrug, can be activated in hypoxic environment. It specifically targets the hypoxic microenvironment of tumors and produces toxic free radicals. However, d

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