A cysteine trapping assay for risk assessment of reactive acyl CoA metabolites.

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DOI:10.1080/00498254.2022.2035016
作者：Nobuyuki Kakutani,?Satoru Kobayashi,?Toshio Taniguchi,?Yukihiro Nomura
文献类型：期刊论文
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Taylor & Francis

Abstract：Some drugs with carboxylic acid moieties can potentially cause rare but severe hepatotoxicity. The reactive chemical species generated by drug metabolism are thought to be one reason for thi

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