Systematic engineering of Micromonospora echinospora cell factory for gentamicin C1a overproduction.

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DOI:10.1016/j.tibtech.2025.12.006
作者：Feng Xu,?Hao Gao,?Rong Ben,?Kaihao Hu,?Yuan Wang,?Ali Mohsin,?Yuanxin Guo,?Xu Li,?Haifeng Hang,?Ju Chu,?Xiwei Tian
文献类型：期刊论文
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Elsevier

Abstract：The clinical importance of gentamicin C1a as a broad-spectrum aminoglycoside antibiotic underscores the need for efficient biomanufacturing strategies. In this study, we developed a systemat

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