Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma

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DOI:10.1101/2023.12.03.569791
作者：Urszula N Wasko, Jingjing Jiang, Alvaro Curiel Garcia, Yingyun Wang, Bianca Lee, Margo Orlen, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Tanner Dalton, M
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Abstract：Broad-spectrum RAS inhibition holds the potential to benefit roughly a quarter of human cancer patients whose tumors are driven by RAS mutations. However, the impact of inhibiting RAS functi

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