Enantioselective Synthesis of Chiral 2,2-Difluoro-spiro[indene- [1,3,4]oxadiazines] by NHC-Catalyzed [4 + 2] Cyclization Reactions.

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DOI:10.1021/acs.orglett.6c00069
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1021/acs.orglett.6c00069

American Chemical Society (ACS)

Abstract：1,3,4-Oxadiazine derivatives represent an essential class of oxadiazine scaffolds that have demonstrated a wide spectrum of applications in modern drug discovery. However, the efficient and

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