Activation of T cell-intrinsic p53 by acetylation elicits antitumor immunity to boost cancer immunotherapy.

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DOI:10.1158/2159-8290.cd-25-0649
作者：Xiaojun Yan,Wenbin Xu,Han Yao,Zhen Wu,Jingyuan Ning,Shidong Zhao,Yajing Liu,Meng Zhang,Dongkui Xu,Zhanlong Shen,Wei Gu,Donglai Wang
文献类型：期刊论文
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American Association for Cancer Research (AACR)

Abstract：Although p53 plays a central role in tumor suppression, how it is regulated in T cells to exert antitumor effects remains unclear. Here, we show that activation of T cell-intrinsic p53 via c

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