Modified Akuamma Alkaloids with Increased Potency at the Mu-opioid Receptor

待确认 20 由小小发布于 2026/2/28 9:17:07

DOI:10.1021/acs.jmedchem.2c01707
作者：Madeline R. Hennessy,?Anna M. Gutridge,?Alexander R. French,?Elizabeth S. Rhoda,?Yazan J. Meqbil,?Meghna Gill,?Yavnika Kashyap,?Kevin Appourchaux,?Barnali Paul,?Zaijie Jim Wang,?Richard M. van Rijn an
文献类型：期刊论文
补充材料：只需要正文

American Chemical Society (ACS)

Abstract：Akuammine (1) and pseudoakuammigine (2) are indole alkaloids found in the seeds of the akuamma tree (Picralima nitida). Both alkaloids are weak agonists of the mu opioid receptor (μOR); howe

应助信息

等待求助人确认

求助人未确认前，本求助不能再次应助。36小时后系统将自动确认应助成功。本求助将自动关闭。

9小时前

guiying70

679b553d144411f1a95034735aa3bc31.pdf

10小时前

Book学术机器人

2026/2/28 9:17:07 未找到该文献，机器人已退出，请等待人工下载

2026/2/28 9:17:07 Book学术AI机器人收到请求，开始寻找文献

2026/2/28 9:17:07 已向机器人发送请求

10小时前

小小发布求助

上一个求助:其它数据库Naturally Fractured Carbonate Reservoir Characterization: A Case Study of a Mature High-Pour Point Oil Field in Hungary 下一个求助:SpringerCD44 is associated with papillary thyroid carcinoma metastasis via potential modulation of the immunosuppressive tumor microenvironment.