Randomized phase 2b dose-escalation trial of stem cell therapy with laromestrocel for aging frailty

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DOI:10.1016/j.stem.2026.01.017
作者：Jorge G. Ruiz, Anthony A. Oliva, Kevin N. Ramdas, Julian Javier, Jeffrey Rosen, Robert Perry, Antonio Blanco, Pedro Ylisastigui, Jeremy Walston, Hidenori Arai, Elena Volpi, Anne B. Newman, Brittany Va
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Elsevier

Abstract：Frailty, a syndrome that decreases healthspan in older individuals, lacks effective therapies. We conducted a randomized, dose-finding clinical trial to test whether human bone marrow-derive

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