基于青蒿素的高效hdac6选择性抑制剂的发现：设计、合成及抗肿瘤评价

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DOI:10.1021/acs.jmedchem.6c00138
作者：Wei Liu, , , Zhongjie Guo, , , Shuhan Sun, , , Youyou He, , , Shihua Li, , , Yue Guan, , , Ge Zhang*, , and , Shengzheng Wang*,&nb
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American Chemical Society (ACS)

Abstract：Beyond their well-established antimalarial effects, artemisinin and its derivatives have demonstrated promising antitumor activity. Herein, a series of novel artemisinin-based histone deacet

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