Development of a Multigram Preparation of Optically Pure (?)-7-(Bromomethylene)-3-amidobicyclo[2.2.1]heptane-2-carboxamide BMT-395137, a Versatile Scaffold for Divergent Drug Discovery Synthesis

已完结 10 由 SDRD 发布于 2026/3/2 15:38:44

DOI:10.1021/acs.oprd.5c00208
作者：Jianqing Li*, Daniel Smith, Lyndon Cornelius, Subramaniam Krishnananthan, Peng Li, Dauh-Rurng Wu, Chetan Padmakar Darne, Ning Li, James Kempson, Shun Su,&n
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1021/acs.oprd.5c00208

American Chemical Society (ACS)

Abstract：This paper describes the development of a synthetic route for the multigram synthesis of (−)-(1R,2S,3R,4R,Z)-7-(bromomethylene)-N-(4-fluoro-3-(trifluoromethyl)phenyl)-3-(2,2,2-trifluoroaceta

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