A shared neoantigen vaccine combined with immune checkpoint blockade for advanced metastatic solid tumors: phase 1 trial interim results

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DOI:10.1038/s41591-024-02851-9
作者：Amy R. Rappaport,?Chrisann Kyi,?Monica Lane,?Meghan G. Hart,?Melissa L. Johnson,?Brian S. Henick,?Chih-Yi Liao,?Amit Mahipal,?Ardaman Shergill,?Alexander I. Spira,?Jonathan W. Goldman,?Ciaran D. Scall
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Abstract：Therapeutic vaccines that elicit cytotoxic T cell responses targeting tumor-specific neoantigens hold promise for providing long-term clinical benefit to patients with cancer. Here we evalua

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