NEK8 kinase-mediated lactate increase impairs antitumor immunity decreasing radiotherapy sensitivity in colorectal cancer.

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DOI:10.1038/s41467-026-70657-z
作者：Mingzhou Li,Yunfei Ni,Jieqiong Wu,Xin Zou,Yining Chen,Junfeng Qiu,Yifang Li,Huayu Cai,Li Wang,Feifei Wang,Hongxia Zhang,Fangyi Han,Jinghao Huang,Zilong Chen,Bingyu Xu,Li Liang
文献类型：期刊论文
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Nature

Abstract：Radiotherapy effectively treats colorectal cancer (CRC), but local recurrence remains common and abscopal effects-regression of tumors distant from irradiated sites-are rarely observed even

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