Late-stage synthesis of C4-fluorinated and C4-trifluoromethylaminated pyridines

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DOI:10.1038/s44160-026-01035-2
作者：Longhui Chen, Chenming Zu, Fengyuan Zhang, Yahui Ding, Yu-Xin Luan, Li Chen, Pingping Tang
文献类型：期刊论文
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Nature

Abstract：Pyridines, as privileged scaffolds in drug design, can exhibit improved metabolic stability and target affinity through the strategic installation of fluorine or trifluoromethylamino groups

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