Paired patient-derived organoids reveal transcription factor-driven epigenetic remodeling in breast cancer metastasis

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DOI:10.1016/j.stem.2026.02.007
文献类型：期刊论文
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Elsevier

Abstract：Breast cancer exhibits marked clinical heterogeneity and dynamic epigenetic reprogramming during tumor progression, yet current subtyping approaches fail to capture molecular changes associa

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