Engineering Styrene Oxide Isomerase Towards Enhanced Chemoenzymatic Synthesis of (S)-Flurbiprofen

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DOI:10.1002/adsc.202400325
作者：Willy W. L. See, Joel P. S. Choo, Lei Du, Zhi Li
文献类型：期刊论文
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Wiley

Abstract：The conventional synthesis of (S)-flurbiprofen, a valuable non-steroidal anti-inflammatory drug (NSAID), involves inefficient chiral resolution with low-yielding multiple reaction steps, or

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