Miniature and versatile genome regulation TnpB-ωRNA toolkits facilitate cancer immunotherapy.

待确认 20 由 aodeman 发布于 2026/4/3 10:00:17

DOI:10.1038/s41467-026-71327-w
作者：Junlin Lu,Jiajian Lai,Liang Cheng,Hengji Zhan,Kaiwen Jie,Chu Liu,Lin Huang,Meifeng Cen,Sen Liu,Zehua Chen,Qiang Zhang,Jianhui Zhang,Jingdie Wu,Bolin Pan,Siting Chen,Jianmei Zhong,Baoqing He,Hui Li,Xu
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1038/s41467-026-71327-w

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Abstract：CRISPR‒Cas systems represent powerful tools for genome regulation. However, the large size of Cas proteins limits their efficient delivery via an adeno-associated virus (AAV), thereby restri

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