ENsiRNA: A Multimodality Method for siRNA-mRNA and Modified siRNA Efficacy Prediction Based on Geometric Graph Neural Network

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DOI:10.1016/j.jmb.2025.169131
作者：Wenchong Tan , Mingshu Dai , Shimin Ye , Xin Tang , Dawei Jiang , Dong Chen , Hongli Du
文献类型：期刊论文
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Elsevier

Abstract：With the rise of small interfering RNA (siRNA) as a therapeutic tool, effective siRNA design is crucial. Current methods often emphasize sequence-related features, overlooking structural inf

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