Overcoming mucus trapping by engineering PEGylated self-nanoemulsions for enhanced oral absorption of a novel AMPK activator

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DOI:10.1016/j.ijpharm.2026.126704
作者：Juan Tao ,?Yuning Wei ,?Mengyu Zhao ,?Zirong Dong ,?Zibo Wei ,?Shuyan Li ,?Jiaxin Zhao ,?Jinlong Yang ,?Jianping Qi
文献类型：期刊论文
补充材料：只需要正文

Elsevier

Abstract：D100B is a first-in-class small-molecule activator of AMP-activated protein kinase (AMPK) that specifically targets the lysosomal pool, enabling precise metabolic regulation with lower syste

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